Microscopic colitis – Inflammatory Bowel Disease

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Microscopic colitis is the general name for the inflammatory bowel disease when there is an inflammatory state of the colon which can be visualized with a microscope by a health care provider. Inflammation is normal response of our body when there is an irritation, injury or infection in the tissues of our body. Rezvera is a unique supplement that promotes normal colon activity, normal bowel movement and aid in digestive health. Rezvera contains 18 natural digestive enzymes helps to prevent bowel disorders.

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TYPES OF MICROSCOPIC COLITIS

There are mainly two types of microscopic colitis that differ in their microscopic view. Most of the medical professional often commonly names them as microscopic colitis as both the types have similar signs, symptoms and treatment. Most of the studies reports that both are different conditions of the same condition.

In both the types of microscopic colitis there is an elevation in the count of lymphocytes which is a type of white blood cells in the inner layers of colon that lines them.

While viewing them separately, the related studies have finalized that

In Lymphocytic colitis the number of the lymphocytes is higher in number and the tissues that line the colon remain in the normal range.

In collagenous colitis the layer of collagen, under the epithelium, a thin threadlike protein builds up and become thicker and thicker crossing the normal range of thickness.

When your physician examines you, there can be chances to view certain area of lymphocyte numbers and collagen thickness in different areas of colon. These kinds of variations signify that there is presence of both types.

CAUSES OF MICROSCOPIC COLITIS

The cause for occurrence of microscopic colitis varies from person to person. There are various risk factors that lead to cause microscopic colitis. But most of the researches finalized that microscopic colitis occur as a result of abnormal immune response to the bacteria flora that are healthy to our body. The other causes that were proposed are:-

  • Infections
  • Certain medications
  • Autoimmune disease
  • Bile acid malabsorption
  • Genetic factors

Infections: Some people who are suffering from microscopic colitis might be after an infection of some harmful bacterial and viral infection. These organisms can produce toxins that irritate and infect the lining of the colon.

Medications: Related studies on medications and microscopic colitis have come up with reports that there exists some link between them as a causative factor also. The most common ones include

  • NSAID’S like aspirin, naproxen, ibuprofen
  • Lansoprzole
  • Ranitidine
  • Sertraline
  • Acarbose
  • Ticlopidine

Autoimmune disease: Some of the people who are suffering from microscopic colitis will also have autoimmune disorders. The most common auto immune disorders that are linked with microscopic colitis are:-

  • Celiac disease
  • Psoriasis
  • Rheumatoid arthritis
  • Thyroid disease like Graves disease and Hashimoto’s disease

Bile acid Malabsorption: Some reports signify that bile acid malabsorption and microscopic colitis are directly linked. The condition is the inability of the body to reabsorb the bile acids completely.

Genetic factors: Although scientist have not yet finalized with a unique gene to microscopic colitis, they have linked certain dozens of genes to the other inflammatory bowel diseases which include ulcerative colitis and crohn’s disease, in which ulcerative colitis is a disease that cause ulcers and inflammation in the inner lining of the colon and crohn’s disease is a disease that can cause irritation and inflammation in any parts of our gastro intestinal track.

WHO ARE MORE PRONE TO MICROSCOPIC COLITIS

You are more likely to get microscopic colitis if you are:-

  • A female
  • 50 years of age or older
  • Already have an autoimmune disease
  • Use medications that are more linked to microscopic disease.
  • Have the habit of smoking cigarettes for chronic period of time

SIGNS AND SYMPTOMS OF MICROSCOPIC COLITIS

Chronic, non bloody and watery diarrhea is the most common symptoms of microscopic colitis. The diarrhea attack can even last for years. But some people can also have long periods of microscopic colitis without diarrhea. A strong urgency to have bowel movement, pain in the abdomen, weight loss, fecal incontinence, dehydration and nausea are the other related symptoms of microscopic colitis. For those lucky ones the symptoms will go away without any attempt of treating the condition.

DIAGNOSIS OF MICROSCOPIC COLITIS

Microscopic colitis id diagnosed by your doctor based on the microscopic findings or findings of the biopsies taken from colon. The pathologist can examine the tissue sample in his/her lab. For many patients, both lymphocytic and collage nous colitis is seen in different areas of large intestine.

To diagnose the condition your doctor will go detail in to the your medical and family history where you will have to open up with the present, past and doubtful medical conditions and the medications that you have been taken. This will be followed by physical examination. He might perform certain medical tests which can include lab, imaging and endoscopy related to intestine to rule out the bowel disease. The lab test will include blood and stool test. The imaging test will include computerized tomography scan and magnetic resonance imaging and upper GI series. The endoscopy of the intestine will include colonoscopy with biopsy, upper Gastro intestinal endoscopy with biopsy and flexible sigmoidoscopy with biopsy.

TREATMENT OF MICROSCOPIC COLITIS

The doctors will prescribe certain medications to control the symptoms. The most common medications prescribed are under the group

  • Anti diarrheal medications
  • Corticosteroids
  • Anti-inflammatory medications
  • Cholestyramine resin
  • Anti-TNF therapies
  • Certain group of antibiotics
  • Immunomodulators

Most of the cases have been treated completely with medications and changes in the diet and lifestyle patterns, although chances for relapses do exist. Some patients will need long term medications and treatments if they are more prone to its relapses.

Surgery is a rare treatment opted for treating microscopic colitis.

DIETARY CHANGES

  • Avoid junk foods
  • Avoid drinking caffeine and artificial sugar fluids
  • Have gluten and milk free diet if you are lactose intolerant.
  • Have a discussion with your doctor and rule out fruits and vegetables that will suit your present condition.

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Originally posted 2015-02-05 00:14:51.

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